ABSTRACT
This study investigated the possible protective effect of
methanol extract of Cassia sieberena leaves (MECS) against high- fat diet (HFD)
induced metabolic syndrome in rats. Forty (40) albino rats were randomized into
4 groups of 10 animals each. Group 1 served as control and the rats were fed
standard rat diet for 90 days. Rats in Group 2 were fed HFD for 90 days. Group
3 rats were fed HFD for 90 days but administered MECS (200 mg/kg b.w) from days
31- 90 while rats in Group 4 were fed HFD and administered MECS (200 mg/kg/day)
concurrently for 90 days. The effects of treatment on some components of
metabolic syndrome (obesity, hyperglycaemia and insulin resistance) were
investigated through the measurement of body weight, fasting blood sugar (FBS),
serum insulin level, total cholesterol (T. Chol.), triacylglyceride (TAG), High
density lipoprotein (HDL) and Low density lipoprotein (LDL) concentrations.
Results showed that administration of the extract for 30 and 90 days
significantly ..........
Read more: http://www.wjpls.org/home/article_abstract/1055 | http://www.wjpls.org/download/article/30082018/1535696664.pdf
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